Monkey IgE ELISA Kits

靶标信息

The IgE gene in monkeys, particularly in cynomolgus monkeys, has garnered significant interest due to its similarities with human IgE. IgE antibodies play a critical role in allergic reactions and are involved in several allergic conditions including asthma and atopic dermatitis. Studies have shown that IgE in cynomolgus monkeys binds to receptors with an affinity similar to human IgE, suggesting these primates as a valuable model for preclinical studies of anti-IgE therapies. This binding capability is crucial for examining therapeutic antibodies that aim to obstruct IgE interactions with receptors on immune cells, thus offering insights into treatment strategies for IgE-mediated allergic responses. The use of monkey models helps in understanding the mechanisms of IgE synthesis and function, providing a bridge in research from mouse models to human clinical applications. Such studies are essential in advancing the development of therapies targeting IgE production and action in allergic diseases.